Basal insulin
refers to the insulin required to control your blood sugar in the absence
of food intake. A cer- tain amount of insulin is always necessary to keep the blood sugar in the normal range, even in the absence
of eating for prolonged
periods. Without any insulin
in
the body, the starch, fat, and protein in the body will break down with severe health consequences, as occurs in people with type 1 diabetes.
The amount of insulin that the body requires in the absence of food intake is known as the basal requirement and it is
pro- vided
by the
one or
two
injections of long-acting
insulin that most patients give themselves each day. If a person is using an insulin pump, then it is covered
by
the basal setting on
the pump. Modern insulin
pumps offer several basal settings in each 24-hour period, as the basal insulin production in a healthy individual
varies over the
course of the
day, being higher in the 2-to 3-hour period before arising in the morning, for
example.
Bolus insulin refers to the insulin required to remove the energy derived from a meal from the bloodstream and into the tissues, to replenish
energy stores. This is typically provided by the short-acting insulin injec- tion given just prior to eating or by the bolus setting
for
patients on an insulin pump. Recently developed and marketed forms of insulin very closely match the pattern of insulin production from the pancreas itself in response to food. In this way, they are able to
Of
course, once it has been delivered to the body, the
insulin cannot distinguish between basal and meal-
derived glucose and so different types of insulin
prepa- ration will overlap with
each other in their action. Distinguishing between the
two requires specialized knowledge and is beyond the scope of this book.
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